Objective: The objective of this study was to evaluate state of hapiness as outcome measure in sleep disorders in PD.

Background: Outcome measures are very important for assessing different complex aspects of non-motor symptoms in Parkinson’s disease (PD). Sleep disorders are a frequent non-motor manifestation among patients with PD, with a major impact on the patient’s well-being and quality of life.

Method: This case-control study enrolled 131 PD patients and 131 controls. Sleep disorders were evaluated through the Parkinson’s Disease Sleep Scale-2 (PDSS-2), Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI) and REM sleep behavior disorder screening questionnaire- Honk Kong (RBDSQ-HK) scale. PD patients self-assessed their state of happiness using the Oxford Happiness Questionnaire (OHQ). Fatigue was evaluated by the Parkinson’s Disease Fatigue Scale (PFS-16), the cognitive function by the Montreal Cognitive Assessment scale (MoCA) and the quality of life by the The Parkinson’s Disease Questionnaire (PDQ-39).

Results: Based on the PDSS-2 score, patients with Parkinson’s were divided into 2 groups: „bad sleepers” (PDSS-2 ≥ 18) and „good sleepers” (PDSS-2 < 18). The state of happiness in “bad sleepers” was lower than in “good sleepers” according to the total average scores of the OHQ (3.63 ± 0.84 vs. 4.40 ± 0.71, p < 0.001). Patients with PD and normal cognitive function (MoCA > 26) are happier than patients with mild (MoCA 18-25) or moderate (MoCA 10-17) cognitive dysfunction (mean OHQ score: 4.33 ± 0.76 vs. 3.67 ± 0.78 vs. 3.08 ± 0.60, p < 0.001). The level of happiness reported by patients with PD and fatigue (PFS-16 ≥3.3) is lower than in patients without fatigue (3.47 vs 4.20, p <0.001). Patients with lower degrees of happiness according to the OHQ present more excessive daytime sleepyness (EDS), insomnia, RBD and fatigue than patients considered “happy” (p < 0.001). Patients with a reduced state of happiness also have a lower quality of life.

Conclusion: The level of happiness of patients with PD decreases as the level of the non-motor symptoms such as sleep disorders, fatigue and cognitive dysfunction increases.

« Back to 2024 International Congress

MDS Abstracts - https://www.mdsabstracts.org/abstract/state-of-happiness-as-outcome-measure-in-sleep-disorders-in-parkinsons-disease/