Objective: Determine Suicide Risk relationship with motor and non motor symptoms in patients with Parkinson´s disease.

Background:  Suicidal ideation is increased in people with Parkinson’s disease (PD).  Studies on the relationship between motor and non-motor symptoms and suicidal ideation in PD are scarce. This study aimed to assess suicidal ideation and its relationship with motor and non-motor symptoms in PD patients.

Method: We studied consecutively 65 patients with PD. Motor symptoms were evaluated with the International Parkinson and Movement Disorder Society-Unified Parkinson’s Disease Rating Scale and Non-motor symptoms with the Non-Motor Symptoms Assessment Scale for PD. Symptom Checklist scale (SCL-90) was also completed by patients. Patients with moderately to extremely scores in SCL-90´s 13 items were considered with positive suicidal ideation

Results: A total of 65 patients with PD were studied, 69.2% (N=45) were male and the mean age was 64.80(SD±10.31). Suicidal ideation was present in 13.8% (N=9) of the patients. Patients with PD and positive suicidal ideation showed more severe non-motor symptoms and motor symptoms (Table 1). Also, patients with suicidal ideation reported higher means of psychoticism (16.11 SD±9.08), paranoid ideation (11.22 SD±5.28) and phobia anxiety (6.33 SD±3.31). Particularly, a higher difference was found in symptoms of depression (32.89 vs 21.85; p=0.001) and anxiety (23.56 vs 15.51; p=0.002).

Conclusion: Our results showed that PD patients with suicidal ideation suffered from severe motor and non-motor symptoms and were associated with depression and anxiety symptoms. Our findings suggest that suicidal ideation in Parkinson’s disease has a multifactorial origin.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/suicide-risk-relationship-with-motor-and-non-motor-symptoms-in-patients-with-parkinsons-disease/