Objective: Objective of this study was to investigate the potential correlation between hemoglobin levels and Parkinson’s disease (PD) severity, and to compare them with a control group of healthy individuals.

Background: Previous studies have suggested a possible link between anemia and Parkinson’s disease (PD). Some studies found that low hemoglobin (Hb) levels were associated with an increased risk of PD. However, the relationship between Hb levels and PD severity is not well understood.

Method: This study included 58 patients with PD (56.9% female, 43.1% male) and 70 healthy controls. Hb levels were measured and compared between different stages of disease severity as measured by the Hoehn and Yahr (H&Y) scale, UPDRS III and between the PD group and the control group. Statistical analyses included the Mann-Whitney test, Kruskal-Wallis test, and Spearman’s correlation test.

Results: The PD group and control group were homogeneous with respect to age (p=0.9). Hb levels did not differ significantly between the different stages of disease severity (p=0.516) or between the PD group and the control group (p=0.7). Additionally, there was no significant correlation between Hb levels and disease severity as measured by the UPDRS III (r=0.3, p=0.6).

Conclusion: These results suggest that Hb level is not significantly correlated with disease severity in patients with PD. However, further research with larger sample sizes is needed to confirm these findings and to better understand the relationship between Hb levels and PD.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/correlation-between-hemoglobin-level-and-disease-severity-in-patients-with-parkinsons-disease/