Category: Technology
Objective: This pilot study investigates the feasibility of using video data to evaluate sit-to-stand transition parameters and explores how people with PD sit-to-stand in a naturalistic setting.
Background: People with Parkinson’s disease (PD) show changes in sit-to-stand transitions which are related to bradykinesia and balance. People with PD experience difficulties initiating the transition, and reduced speed from seat-off to fully erect posture. Impairment in performance of sit-to-stand transitions is linked to reduced functional independence and physical inactivity. Sit-to-stand transition episodes occur frequently in the indoor setting, making their study amenable at home. Datasets showing free-living real world sit-to-stand episodes with video ground truth in PD are uncommon and potentially valuable in understanding this functionally relevant movement.
Method: 12 people with PD and 12 control participants were recruited. While the participants stayed in a home-like setting for five days in pairs, color video was captured from wall-mounted cameras for around two hours per day. This video data recorded both free-living and observed clinical assessments, and sit-to-stand episodes were quantified by clinician raters. Statistical techniques were used to evaluate the correlation between sit-to-stand parameters, the presence of PD or control and disease severity.
Results: The PD cohort had longer sit-to-stand episode durations and slower transition speed than the control cohort. Sit-to-stand episode duration positively correlated with disease severity markers. There was an inverse correlation between sit-to-stand transition duration and speed.
Conclusion: We demonstrate the feasibility of creating a real-world video dataset capturing and quantifying sit-to-stand transitions. We present results from free-living, offering insight into how people with PD sit-to-stand in a home setting. We explore the utility of measuring both sit-to-stand transition duration and speed as potential digital biomarkers of PD progression.
To cite this abstract in AMA style:
C. Morgan, A. Masullo, H. Isotalus, E. Tonkin, M. Mirmehdi, F. Jovan, T. Whone, G. Oikonomou, R. Mcconville, G. Tourte, K. Kinnunen, I. Craddock. Real-world sit-to-stand evaluation [abstract]. Mov Disord. 2022; 37 (suppl 2). https://www.mdsabstracts.org/abstract/real-world-sit-to-stand-evaluation/. Accessed May 15, 2025.« Back to 2022 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/real-world-sit-to-stand-evaluation/