Objective:
1. To determine the feasibility and logistics of conducting a non-contact boxing exercise program for PD patients.
2. To determine the tolerability of the program.
3. To determine the safety of the program.

Background: Preliminary evidence suggests non-contact boxing exercise is feasible and possibly beneficial for Parkinson Disease (PD). Current studies lack detailed description of component elements and documentation of exercise intensity. There are few data on heart rate targets and rates of perceived exertion; information which is critical for quantifying dose.  We present the protocol of FIGHT-PD; which explores the feasibility, tolerability and safety of a non-contact boxing exercise program for PD, developed by a neurologist (who has PD), a professional boxing trainer, a neurophysiotherapist and exercise physiologists.

Method: Over 15 weeks, three 30-60 minute workouts per week will be conducted in three, 4 week blocks separated by an active recovery week. Block one focuses on technique; the second escalates the physical intensity, and the third adds cognitive challenges. Rate of perceived physical and mental exertion (RPE) will be measured by the Borg scale and heart rate recorded by Polar monitors. Numerous standardised PD scales and a body chart discomfort scale will be administered, monitoring the development of pain or injuries. These observations will provide the primary outcomes of tolerability and safety, and secondary outcomes of quantified heart rate as a measure of exercise intensity, and quality of life measure including mood, sleep and fatigue. Feasibility details including recruitment, retention and adherence rates will be measured.

Results: The study has received ethics approval, screening has commenced, and some interim results should be available by September 2021.

Conclusion: This trial should provide essential details to plan future exercise studies utilising non-contact boxing, including descriptions of specific exercises required to meet heart rate targets and levels of perceived physical and mental exertion. Thresholds for “forced exercise” will be determined.
An previous version of this abstract has been submitted for the Australian and New Zealand association of Neurologists meeting (May 18-21).

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