Objective: Compare safety, tolerability, efficiency and efficacy of DBS (VIM DBS) for tremor in Parkinson’s disease (PD) and Non Parkinsonian Patients over 25 years.

Background: Deep brain stimulation (DBS) has been utilized to treat various symptoms in patients suffering from movement disorders such as Parkinson’s disease, dystonia, and essential tremor. The authors present analysis of DBS for tremor control, in whom electrodes (uni and bilateral) for DBS were implanted in the ventral intermediate nucleus (VIM) of the thalamus.

Method: Forty patients with disabling tremor, with drug-resistant spite of optimum therapeutic trials with poor response were referred to do surgery. 30 patients had bilateral essential tremor. These patients were implanted with electrodes for DBS Activa. Ten patients had unilateral parkinsonian tremor and they received unilateral implantation of model (SC DBS).

Results: All forty patients showed relieve of the tremor symptoms with significant tremor control seen at the scores. There were no definite adverse events after the electrodes implants for DBS, the only ones were all transient and promptly reversed after the adjustment of the parameters.

Conclusion: The results the authors found in this study indicate that VIM-Stimulation is effective for tremor control either parkinsonian or essential tremor. It has the advantage of be bilateral with less risk than VIM ablations. The results correlate with the data in the literature.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/deep-brain-stimulation-of-vim-thalamic-nucleus-for-tremor-control/